
产品货号:
Z31791
中文名称:
DCLK1抗体
英文名称:
Anti-DCLK1 Antibody (Clone#OTI1F8)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DCLK1 Antibody (Clone#OTI1F8) |
指标别名 | DCAMKL1;DCDC3A;DCLK;DCLK1;doublecortin like kinase 1;KIAA0369 |
克隆性 | Monoclonal |
检验物种 | human,mouse |
应用范围 | WB,IHC |
基因名称 | DCLK1 |
克隆号 | OTI1F8 |
抗体来源 | Mouse |
抗体类型 | IgG2b |
免疫原 | Human recombinant protein fragment corresponding to amino acids 193-492 of human DCLK1 (NP_004725) produced in E.coli. |
实际分子量 | 80.9KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | This gene encodes a member of the protein kinase superfamily and the doublecortin family.The protein encoded by this gene contains two N-terminal doublecortin domains,which bind microtubules and regulate microtubule polymerization,a C-terminal serine/threonine protein kinase domain,which shows substantial homology to Ca2+/calmodulin-dependent protein kinase,and a serine/proline-rich domain in between the doublecortin and the protein kinase domains,which mediates multiple protein-protein interactions.The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity.The encoded protein is involved in several different cellular processes,including neuronal migration,retrograde transport,neuronal apoptosis and neurogenesis.This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities.Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported,but the full-length nature and biological validity of some variants have not been defined.These variants encode different isoforms,which are differentially expressed and have different kinase activities. |
Uniprot ID | O15075 |
基因名全称 | Serine/threonine-protein kinase DCLK1 |
推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:500 |
相关搜索:DCLK1抗体,DCLK1单抗,Anti-DCLK1 Antibody (Clone#OTI1F8)